DIY aquarium question: Acrylic + Glass?

This is a bit off-topic, but I think there are a lot of people here with a lot more experience building aquariums and with these materials than I am...

I am working out a design for a small ~6-10 gallon tank that after working out some of the initial design details in Google SketchUp Pro, I think would be best served as a combination of glass and acrylic... if one can combine these.

Can a pane of acrylic be assembled with glass using silicone as if it were just another pane of glass? I would reason so, but would love to hear anyone's experiences.

 

This is for a small, low-light tank. I wanted the background to be drilled for an overflow, and black. Since it's much simpler to drill acrylic, and black acrylic is available, it seemed somewhat reasonable that that rear pane could just be acrylic and the rest glass.

Glass is cheaper ($1/ft^{2} from glasscages.com) than acrylic (~$3/ft^{2} from glasscages.com). I'm willing to compromise price for easier manufacture by not having to use a glass drill, and then not having to paint or "paper" the rear panel.

So, as per my original message, is there anything about a butt joint between glass and acrylic with a silicone caulk seal that anyone might have experience with?

 

Sorry, I thought I'd mentioned the usage. It's not for a typical planted tank. It's partly for an experiment with a "planted killifish" tank. I want to make 4+ of these tanks for a rack with overflow for easy water changes. I was trying to maximize some size parameters for the given shelf. And while I've drilled many tanks, it is a pain in the ass!

Well, thought I'd ask and see before wasting any time or money. Thanks for all the input!