Obviously, your venturi loop is working well and sucking undissolved CO2 back into the pump -- maybe it's working a little too well! I assume you set the venturi loop inlet down low enough, as was recommended. Also, hopefully your Rio's outlet is pointed down at an angle and you are getting a good downward circulation. If there isn't a good turbulence with a downward flow, I could see the CO2 building up gradually to the venturi loop and then overwhelming it, once it finally got there.
How many bubbles per second of CO2 are you sending into the reactor? These are nice little reactors, but I'm sure they have their limits on how much CO2 they can take in. I can't remember how large your tank is, but if it is very big, you might have to split your CO2 and send it to 2 reactors. Of course, if it comes to that, it might be better just to use a different method than the internal reactor.