I could be completely off base here, but I just added some Melafix and Pimafix to my tank to treat a sick clown loach and was amazed by the bubbles produced by my Atomic CO2 diffuser. These additives seem to have a "soapy" quality to them that is allowing the CO2 bubbles to become smaller and more abundant/last longer. I dont know the exact science behind this and it may not be aiding in the dispersal of CO2 but it sure as heck looks like it.